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Datamonkey Documentation

Datamonkey is a free, public web application for evolutionary sequence analysis, powered by HyPhy. It provides a suite of methods for detecting natural selection, recombination, and other evolutionary processes from coding sequence alignments.

Guide

Methods

  • General Information — overview and how to choose a method
  • aBSREL — adaptive branch-site test for episodic diversification
  • B-STILL — Bayesian test for invariant sites
  • BGM — Bayesian graphical models for coevolving sites
  • BUSTED — branch-site unrestricted statistical test for episodic diversification
  • Contrast-FEL — test for differences in selective pressures between groups
  • FADE — FUBAR approach to directional evolution
  • FEL — fixed effects likelihood for site-wise dN/dS estimation
  • FUBAR — fast unconstrained Bayesian approximation
  • GARD — genetic algorithm for recombination detection
  • MEME — mixed effects model of evolution for episodic selection
  • MSS — multiple synonymous substitution models
  • MULTI-HIT — accounting for multiple simultaneous substitutions
  • NRM — nucleotide rate matrix analysis
  • PRIME — property-informed models of evolution
  • RELAX — test for relaxation or intensification of selection
  • SLAC — single-likelihood ancestor counting

Resources

LicenseDatamonkey Status

Released under the MIT License.